Bioseparations principles and techniques pdf

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Biological products are important for many applications including biotransformations, diagnostics, research and development, and in the food, pharmaceutical, and cosmetics industries. For certain applications, biological products can be used as crude extracts with little or no purication. However, biopharmaceuticals typically require exceptional purity, making downstream processing a critical component of the overall process. From the regulatory viewpoint, the production process itself denes the biopharmaceutical product rendering proper denition of effective and efcient downstream processing steps crucial early in process development. Currently, proteins are the most important biopharmaceuticals. The history of their development as industrial products goes back more than half a century.

2. Principles of Bioseparations Engineering natural sources and these are simply recovered using appropriate techniques e.g. manufacture of plasma proteins.
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