Genetic Counseling for Women
Chromosome Abnormalities and Genetic Counseling: Fourth Edition
This book first appeared in and rapidly became an indispensible resource for genetic counselling students, medical geneticists and cytogeneticists alike. The original authors, RJ Mckinlay Gardner a medical geneticist of some 40 years experience and GR Sutherland a cytogeneticist and molecular geneticist have been joined by LG Shaffer a micro-array specialist to cover the additional molecular techniques in use in the modern cytogenetics laboratory. The move away from classical microscopy into molecular methodologies, predicted for some time, is now actually happening. Smaller and subtler abnormalities can be detected. We know a lot more but much yet to know about normal genomic variation. Chromosomal testing of embryos before implantation, while not commonplace, is no longer regarded as extraordinary … Meiosis is as vulnerable as it has always been. Chromosomes continue to undergo rearrangement.
R.J.M Gardner, Grant R Sutherland, and Lisa G. Shaffer
Correspondence Address : Prof. The chromosomal abnormality, especially balanced translocation rearrangement in either parent, is the important cause of recurrent spontaneous abortion. Aims: The aim of this study was to investigate the role and prevalence of chromosomal anomalies in recurrent miscarriages. The results will be helpful for counseling and make the decision for alternative options and precaution for the affected couples and also support to make a national database. Settings and Design: The present retrospective study was carried out in couples individuals having the history of three or more recurrent spontaneous abortion. The cytogenetic analysis was done in all individuals using G-banding and karyotyping. Results: Out of couples, 17 couples 9.
This new edition of Chromosome Abnormalities and Genetic Counseling is a thoroughly updated ands richly-illustrated resource, combining basic concepts of chromosomal analysis with practical applications of recent advances in molecular cytogentics. It gives counselors the information that will enable them to help concerned parents accommodate and adapt to their particular chromosomal challenges and to determine what may be, for them, the best course of action. M Gardner, author Auckland City Hospital. Lisa G. Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription. Please subscribe or login to access full text content.